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o In late stages of the disease, normal architecture may be lost.59 Additionally, atrophy and fusion of the labia minora, constriction of the vaginal orifice (kraurosis), synechiae, ecchymoses, fissures, and telangiectases may be noted. Squamous cell carcinoma develops in 3-6% of women affected by vulvar lichen sclerosus, which is therefore now regarded as a preneoplastic condition.3,60,61 The presence and the duration of symptoms and the loss of vulvar architecture are not useful indicators of potential cancer risk. http://buymedsonline.org/products/buy-nizoral-online.htm - http://buymedsonline.org/products/buy-nizoral-online.htm
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